BDBM50121832 (R)-3-Cyclobutyl-2-{(S)-3-(3-fluoro-phenyl)-4-[4-(3-phenyl-propyl)-piperidin-1-ylmethyl]-pyrrolidin-1-yl}-propionic acid::(R)-3-cyclobutyl-2-((3S,4S)-3-(3-fluorophenyl)-4-((4-(3-phenylpropyl)piperidin-1-yl)methyl)pyrrolidin-1-yl)propanoic acid::CHEMBL278085

SMILES OC(=O)[C@@H](CC1CCC1)N1C[C@H](CN2CCC(CCCc3ccccc3)CC2)[C@H](C1)c1cccc(F)c1

InChI Key InChIKey=OMBXIIQERBKCSZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50121832   

TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50121832((R)-3-cyclobutyl-2-((3S,4S)-3-(3-fluorophenyl)-4-(...)
Affinity DataIC50: 0.5nMAssay Description:Ability to displace [125I]- labeled MIP-1alpha from CCR5 receptor expressed on CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50121832((R)-3-cyclobutyl-2-((3S,4S)-3-(3-fluorophenyl)-4-(...)
Affinity DataIC50: 0.5nMAssay Description:Displacement of [125I]MIP1alpha from human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed