BDBM50121744 1-((S)-1-Methyl-pyrrolidin-2-ylmethyl)-4-pyridin-3-ylmethyl-piperazine::CHEMBL267915

SMILES CN1CCC[C@H]1CN1CCN(Cc2cccnc2)CC1

InChI Key InChIKey=ULRNQAZROUDCII-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50121744   

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50121744(1-((S)-1-Methyl-pyrrolidin-2-ylmethyl)-4-pyridin-3...)
Affinity DataKi:  3.17E+4nMAssay Description:Binding affinity towards alpha4-beta2 measured by using the inhibition of [3H]NIC binding to rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50121744(1-((S)-1-Methyl-pyrrolidin-2-ylmethyl)-4-pyridin-3...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity towards alpha-7 neuronal nicotinic acetylcholine receptor (nAChRs) measured by using the inhibition of [3H]-MLA binding to whole bra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed