BDBM50121552 CHEMBL356669::Morpholine-4-carboxylic acid [1-(1-cyano-3-phenyl-propylcarbamoyl)-2-phenyl-ethyl]-amide

SMILES O=C(N[C@@H](CCc1ccccc1)C#N)[C@H](Cc1ccccc1)NC(=O)N1CCOCC1

InChI Key InChIKey=SAJDFWBRNFJSFM-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50121552   

TargetCathepsin S(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50121552(Morpholine-4-carboxylic acid [1-(1-cyano-3-phenyl-...)
Affinity DataKd:  60nMAssay Description:Equilibrium dissociation constant determined using fluorescence based competitive binding assay towards Cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50121552(Morpholine-4-carboxylic acid [1-(1-cyano-3-phenyl-...)
Affinity DataIC50: 173nMAssay Description:Inhibitory concentration against human recombinant Cathepsin S expressed in baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed