BDBM50121418 CHEMBL119078::Lithium; 2-(2,4-dichloro-benzoylamino)-5-quinolin-8-yl-benzoate

SMILES [O-]C(=O)c1cc(ccc1NC(=O)c1ccc(Cl)cc1Cl)-c1cccc2cccnc12

InChI Key InChIKey=JNKVAVBHDDQNPH-UHFFFAOYSA-M

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50121418   

LigandPNGBDBM50121418(Lithium; 2-(2,4-dichloro-benzoylamino)-5-quinolin-...)
Affinity DataEC50:  300nMAssay Description:Transactivation potency was measured by luciferase activity in Caco- 2/TC7 cells transiently co-transfected for the fusion-protein Gal4-PPAR gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50121418(Lithium; 2-(2,4-dichloro-benzoylamino)-5-quinolin-...)
Affinity DataEC50: >1.00E+5nMAssay Description:Transactivation potency was measured by luciferase activity in Caco- 2/TC7 cells transiently co-transfected for the fusion-protein Gal4-PPAR alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50121418(Lithium; 2-(2,4-dichloro-benzoylamino)-5-quinolin-...)
Affinity DataKi:  700nMAssay Description:Ligand binding affinity was determined by displacement of a tritiated tracer by the unlabeled compound to a GST-PPAR fusion protein for Peroxisome pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50121418(Lithium; 2-(2,4-dichloro-benzoylamino)-5-quinolin-...)
Affinity DataKi: >1.00E+5nMAssay Description:Ligand binding affinity was determined by displacement of a tritiated tracer by the unlabeled compound to a GST-PPAR fusion protein for Peroxisome pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed