BDBM50121414 CHEMBL333890::Lithium; 2-(2,4-dichloro-benzoylamino)-5-(2-thiophen-3-yl-ethoxy)-benzoate

SMILES [O-]C(=O)c1cc(OCCc2ccsc2)ccc1NC(=O)c1ccc(Cl)cc1Cl

InChI Key InChIKey=KHZMMMNYHGINGK-UHFFFAOYSA-M

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50121414   

LigandPNGBDBM50121414(Lithium; 2-(2,4-dichloro-benzoylamino)-5-(2-thioph...)
Affinity DataEC50:  3.80E+3nMAssay Description:Transactivation potency was measured by luciferase activity in Caco- 2/TC7 cells transiently co-transfected for the fusion-protein Gal4-PPAR alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50121414(Lithium; 2-(2,4-dichloro-benzoylamino)-5-(2-thioph...)
Affinity DataEC50:  800nMAssay Description:Transactivation potency was measured by luciferase activity in Caco- 2/TC7 cells transiently co-transfected for the fusion-protein Gal4-PPAR gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50121414(Lithium; 2-(2,4-dichloro-benzoylamino)-5-(2-thioph...)
Affinity DataKi:  600nMAssay Description:Ligand binding affinity was determined by displacement of a tritiated tracer by the unlabeled compound to a GST-PPAR fusion protein for Peroxisome pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50121414(Lithium; 2-(2,4-dichloro-benzoylamino)-5-(2-thioph...)
Affinity DataKi:  2.00E+4nMAssay Description:Ligand binding affinity was determined by displacement of a tritiated tracer by the unlabeled compound to a GST-PPAR fusion protein for Peroxisome pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed