BDBM50121320 4-[4,4,4-trifluoro-1-(4-hydroxyphenyl)-2-phenylbut-1-enyl]phenol::CHEMBL357283

SMILES [#8]-c1ccc(cc1)-[#6](=[#6](\[#6]C(F)(F)F)-c1ccccc1)\c1ccc(-[#8])cc1

InChI Key InChIKey=UEFJFJIZCASNSH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50121320   

TargetEstrogen receptor(Human)
Free University of Berlin

Curated by ChEMBL
LigandPNGBDBM50121320(4-[4,4,4-trifluoro-1-(4-hydroxyphenyl)-2-phenylbut...)
Affinity DataIC50: 9nMAssay Description:Antiestrogenic activity in MCF-7-2a cells as concentration required to reduce estradiol effect by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed