BDBM50121213 CHEMBL3622371

SMILES O=C(NCc1ccccc1)[C@H](CCCCNC1CC1c1ccccc1)NC(=O)c1ccccc1

InChI Key InChIKey=ZKIYEAILMJBDRZ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50121213   

TargetLysine-specific histone demethylase 1A(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50121213(CHEMBL3622371)
Affinity DataIC50: 300nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50121213(CHEMBL3622371)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of MAO-A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2016
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 2(Human)
Waseda University

Curated by ChEMBL
LigandPNGBDBM50121213(CHEMBL3622371)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of recombinant human LSD2 using H3K4 peptide as substrate assessed as decrease in H3K4 demethylation after 1 hr by mass spectroscopic anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2017
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50121213(CHEMBL3622371)
Affinity DataIC50: 300nMAssay Description:Inhibition of human LSD1 using H3K4 peptide as substrate by peroxidase-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2017
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50121213(CHEMBL3622371)
Affinity DataIC50: 300nMAssay Description:Inhibition of N-terminal hexahistidine-tagged human LSD1 (1 to 852 amino acids) expressed in Escherichia coli BL21 (DE3) cells using H3K4me2 peptide ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed