BDBM50121176 3-(2'-oxo-1',2'-dihydrospiro[cyclopentane-1,3'-indol]-5'-yl)benzonitrile::CHEMBL117573

SMILES O=C1Nc2ccc(cc2C11CCCC1)-c1cccc(c1)C#N

InChI Key InChIKey=QOLHBLXTCPSWBK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50121176   

TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50121176(3-(2'-oxo-1',2'-dihydrospiro[cyclopentane-1,3'-ind...)
Affinity DataIC50: 21nMAssay Description:Inhibition of 3 nM [3H]R5020 binding to progesterone receptor of human T47D cell cytosolMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed