BDBM50121172 5-fluoro-3-(2'-oxo-1',2'-dihydrospiro[cyclohexane-1,3'-indol]-5'-yl)benzonitrile::CHEMBL333484

SMILES Fc1cc(cc(c1)-c1ccc2NC(=O)C3(CCCCC3)c2c1)C#N

InChI Key InChIKey=KRVNQLOXQIJQEY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50121172   

TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50121172(5-fluoro-3-(2'-oxo-1',2'-dihydrospiro[cyclohexane-...)
Affinity DataIC50: 20nMAssay Description:Inhibition of 3 nM [3H]R5020 binding to progesterone receptor of human T47D cell cytosolMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50121172(5-fluoro-3-(2'-oxo-1',2'-dihydrospiro[cyclohexane-...)
Affinity DataIC50: 51nMAssay Description:Inhibition of 3 nM [3H]R5020 binding to progesterone receptor of human T47D cell cytosolMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed