BDBM50121164 3-(3,3-Dimethyl-2-oxo-2,3-dihydro-1H-indol-5-yl)-benzonitrile::3-(3,3-dimethyl-2-oxoindolin-5-yl)benzonitrile::CHEMBL117187

SMILES CC1(C)C(=O)Nc2ccc(cc12)-c1cccc(c1)C#N

InChI Key InChIKey=WZZPSUKZMZKXTQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50121164   

TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50121164(3-(3,3-dimethyl-2-oxoindolin-5-yl)benzonitrile | 3...)
Affinity DataIC50: 27nMAssay Description:Inhibition of 3 nM [3H]R5020 binding to progesterone receptor of human T47D cell cytosolMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50121164(3-(3,3-dimethyl-2-oxoindolin-5-yl)benzonitrile | 3...)
Affinity DataIC50: 27nMAssay Description:Antagonist activity at human PR expressed in human T47D cells assessed as inhibition of progesterone induced alkaline phosphataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed