BDBM50121078 CHEMBL3622063

SMILES NS(=O)(=O)Oc1ccc2cc(CN(c3ccc(cc3)C#N)n3cnnc3)ccc2c1Cl

InChI Key InChIKey=ZKZPGLHMNDLJIP-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50121078   

TargetSteryl-sulfatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50121078(CHEMBL3622063)
Affinity DataIC50: 26nMAssay Description:Inhibition of STS activity (unknown origin) expressed in JEG-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2016
Entry Details Article
PubMed
TargetAromatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50121078(CHEMBL3622063)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of aromatase (unknown origin) expressed in JEG-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2016
Entry Details Article
PubMed
TargetAromatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50121078(CHEMBL3622063)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50121078(CHEMBL3622063)
Affinity DataIC50: 26nMAssay Description:Inhibition of sulfatase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetAromatase(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50121078(CHEMBL3622063)
Affinity DataIC50: 26nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed