BDBM50121047 5-Fluoro-2-[3-(1-hydroxy-ethyl)-2,6-diisopropyl-5-propyl-pyridin-4-yl]-phenol::CHEMBL323913

SMILES CCCc1c(nc(C(C)C)c(C(C)O)c1-c1ccc(F)cc1O)C(C)C

InChI Key InChIKey=WPUCRISSEKWRQP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50121047   

TargetGlucagon receptor(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50121047(5-Fluoro-2-[3-(1-hydroxy-ethyl)-2,6-diisopropyl-5-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity of second diastereomer (D2) against human glucagon receptor was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50121047(5-Fluoro-2-[3-(1-hydroxy-ethyl)-2,6-diisopropyl-5-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity of second diastereomer (D2) against human glucagon receptor was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50121047(5-Fluoro-2-[3-(1-hydroxy-ethyl)-2,6-diisopropyl-5-...)
Affinity DataIC50: 10nMAssay Description:Binding affinity of second enantiomer (E2) against human glucagon receptor was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50121047(5-Fluoro-2-[3-(1-hydroxy-ethyl)-2,6-diisopropyl-5-...)
Affinity DataIC50: 18nMAssay Description:Binding affinity of first diastereomer (D1) against human glucagon receptor was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed