BDBM50121045 2-[3-Ethyl-5-(1-hydroxy-ethyl)-2,6-diisopropyl-pyridin-4-yl]-5-fluoro-phenol::CHEMBL114762

SMILES CCc1c(nc(C(C)C)c(C(C)O)c1-c1ccc(F)cc1O)C(C)C

InChI Key InChIKey=HMAMWDQIZIGXCH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50121045   

TargetGlucagon receptor(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50121045(2-[3-Ethyl-5-(1-hydroxy-ethyl)-2,6-diisopropyl-pyr...)
Affinity DataIC50: 16nMAssay Description:Binding affinity of second enantiomer (E2) against human glucagon receptor was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50121045(2-[3-Ethyl-5-(1-hydroxy-ethyl)-2,6-diisopropyl-pyr...)
Affinity DataIC50: 16nMAssay Description:Binding affinity of second enantiomer (E2) against human glucagon receptor was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50121045(2-[3-Ethyl-5-(1-hydroxy-ethyl)-2,6-diisopropyl-pyr...)
Affinity DataIC50: 5.00E+3nMAssay Description:Binding affinity of first enantiomer (E1) against human glucagon receptor was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50121045(2-[3-Ethyl-5-(1-hydroxy-ethyl)-2,6-diisopropyl-pyr...)
Affinity DataIC50: 20nMAssay Description:Binding affinity of first diastereomer (D1) against human glucagon receptor was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed