BDBM50121044 CHEMBL116041::[(S)-2-(3-Fluoro-phenyl)-1-((5S,6R)-4,4,7-trioxo-4lambda*6*-thia-1-aza-bicyclo[3.2.0]hept-6-ylcarbamoyl)-ethyl]-carbamic acid benzyl ester

SMILES Fc1cccc(C[C@H](NC(=O)OCc2ccccc2)C(=O)N[C@H]2[C@H]3N(CCS3(=O)=O)C2=O)c1

InChI Key InChIKey=FNEUKBQFZSGMQF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50121044   

TargetCathepsin K(Human)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121044([(S)-2-(3-Fluoro-phenyl)-1-((5S,6R)-4,4,7-trioxo-4...)
Affinity DataIC50: 6nMAssay Description:Inhibition of Cbz-Phe-Arg-AMC binding to Cathepsin K cysteine proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Rat)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121044([(S)-2-(3-Fluoro-phenyl)-1-((5S,6R)-4,4,7-trioxo-4...)
Affinity DataIC50: 3nMAssay Description:Inhibition of Cbz-Phe-Arg-AMC binding to Cathepsin L cysteine proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121044([(S)-2-(3-Fluoro-phenyl)-1-((5S,6R)-4,4,7-trioxo-4...)
Affinity DataIC50: 8nMAssay Description:In vitro Inhibitory activity against Cathepsin S cysteine protease by using Cbz-Val-Arg-AMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121044([(S)-2-(3-Fluoro-phenyl)-1-((5S,6R)-4,4,7-trioxo-4...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity of Cbz-Phe-Arg-AMC against Cathepsin B cysteine proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed