BDBM50121028 CHEMBL113761::[(S)-1-((S)-7-Oxo-4-oxa-1-aza-bicyclo[3.2.0]hept-6-ylcarbamoyl)-2-phenyl-propyl]-carbamic acid benzyl ester

SMILES O=C(N[C@@H](Cc1ccccc1)C(=O)N[C@H]1[C@H]2OCCN2C1=O)OCc1ccccc1

InChI Key InChIKey=VYRSXJDNPISAMG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50121028   

TargetCathepsin K(Human)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121028([(S)-1-((S)-7-Oxo-4-oxa-1-aza-bicyclo[3.2.0]hept-6...)
Affinity DataIC50: 1.63E+3nMAssay Description:In vitro Inhibitory activity against Cathepsin K cysteine protease by using Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121028([(S)-1-((S)-7-Oxo-4-oxa-1-aza-bicyclo[3.2.0]hept-6...)
Affinity DataIC50: 430nMAssay Description:In vitro Inhibitory activity against Cathepsin S cysteine protease by using Cbz-Val-Arg-AMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121028([(S)-1-((S)-7-Oxo-4-oxa-1-aza-bicyclo[3.2.0]hept-6...)
Affinity DataIC50: 1.76E+3nMAssay Description:In vitro Inhibitory activity against Cathepsin B cysteine protease by using Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Rat)
Currently Naeja Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50121028([(S)-1-((S)-7-Oxo-4-oxa-1-aza-bicyclo[3.2.0]hept-6...)
Affinity DataIC50: 85nMAssay Description:In vitro Inhibitory activity against Cathepsin L cysteine protease by using Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed