BDBM50120739 (7-Chloro-quinolin-4-yl)-(2-morpholin-4-yl-ethyl)-amine::7-chloro-N-(2-morpholinoethyl)quinolin-4-amine::CHEMBL148139

SMILES Clc1ccc2c(NCCN3CCOCC3)ccnc2c1

InChI Key InChIKey=YWSYGJGUZGAYSR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50120739   

TargetHistidine-rich protein PFHRP-II(malaria parasite P. falciparum)
The University of Liverpool

Curated by ChEMBL
LigandPNGBDBM50120739((7-Chloro-quinolin-4-yl)-(2-morpholin-4-yl-ethyl)-...)
Affinity DataIC50: 1.02E+5nMAssay Description:Inhibition of beta-hematin formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Minas Gerais

Curated by ChEMBL
LigandPNGBDBM50120739((7-Chloro-quinolin-4-yl)-(2-morpholin-4-yl-ethyl)-...)
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-phe-Arg-amidomethylcoumarin as substrate by fluorometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2019
Entry Details Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Minas Gerais

Curated by ChEMBL
LigandPNGBDBM50120739((7-Chloro-quinolin-4-yl)-(2-morpholin-4-yl-ethyl)-...)
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of Trypanosoma cruzi CruzainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Universidade Federal Do Rio Grande Do Sul

Curated by ChEMBL
LigandPNGBDBM50120739((7-Chloro-quinolin-4-yl)-(2-morpholin-4-yl-ethyl)-...)
Affinity DataIC50: 6.10E+4nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed