BDBM50120694 CHEMBL356975::N-Hydroxy-2-(3-methyl-2-oxo-3-phenyl-pyrrolidin-1-yl)-propionamide

SMILES C[C@@H](N1CC[C@](C)(C1=O)c1ccccc1)C(=O)NO

InChI Key InChIKey=GDUSADXUOJTTQS-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50120694   

LigandPNGBDBM50120694(N-Hydroxy-2-(3-methyl-2-oxo-3-phenyl-pyrrolidin-1-...)
Affinity DataIC50: 2.20E+3nMAssay Description:Affinity for Tumor necrosis factor alpha converting enzyme (TACE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50120694(N-Hydroxy-2-(3-methyl-2-oxo-3-phenyl-pyrrolidin-1-...)
Affinity DataKi:  108nMAssay Description:Affinity for Matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50120694(N-Hydroxy-2-(3-methyl-2-oxo-3-phenyl-pyrrolidin-1-...)
Affinity DataKi:  221nMAssay Description:Affinity towards Matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50120694(N-Hydroxy-2-(3-methyl-2-oxo-3-phenyl-pyrrolidin-1-...)
Affinity DataKi:  242nMAssay Description:Affinity towards Matrix metalloprotease-9 (MMP-9)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed