BDBM50120686 (R)-N-hydroxy-2-((S)-3-(4-isobutylphenyl)-3-methyl-2-oxopyrrolidin-1-yl)propanamide::CHEMBL148118::N-Hydroxy-2-[3-(4-isobutyl-phenyl)-3-methyl-2-oxo-pyrrolidin-1-yl]-propionamide

SMILES CC(C)Cc1ccc(cc1)[C@]1(C)CCN([C@H](C)C(=O)NO)C1=O

InChI Key InChIKey=NIUYUCAJYPRIRB-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50120686   

LigandPNGBDBM50120686(N-Hydroxy-2-[3-(4-isobutyl-phenyl)-3-methyl-2-oxo-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Affinity for Tumor necrosis factor alpha converting enzyme (TACE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50120686(N-Hydroxy-2-[3-(4-isobutyl-phenyl)-3-methyl-2-oxo-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50120686(N-Hydroxy-2-[3-(4-isobutyl-phenyl)-3-methyl-2-oxo-...)
Affinity DataKi:  586nMAssay Description:Affinity towards Matrix metalloprotease-9 (MMP-9)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50120686(N-Hydroxy-2-[3-(4-isobutyl-phenyl)-3-methyl-2-oxo-...)
Affinity DataKi:  701nMAssay Description:Affinity for Matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50120686(N-Hydroxy-2-[3-(4-isobutyl-phenyl)-3-methyl-2-oxo-...)
Affinity DataKi:  4.00E+3nMAssay Description:Affinity towards Matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed