BDBM50120667 Acetic acid 4-(2-{(S)-2-[5-[2-(2-aza-bicyclo[2.2.2]oct-2-yl)-1,1-dimethyl-2-oxo-ethyl]-2-(3,5-dimethyl-phenyl)-1H-indol-3-yl]-propylamino}-ethyl)-pyridin-2-ylmethyl ester::CHEMBL115365

SMILES C[C@H](CNCCc1ccnc(COC(C)=O)c1)c1c([nH]c2ccc(cc12)C(C)(C)C(=O)N1CC2CCC1CC2)-c1cc(C)cc(C)c1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50120667   

TargetGonadotropin-releasing hormone receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50120667(Acetic acid 4-(2-{(S)-2-[5-[2-(2-aza-bicyclo[2.2.2...)
Affinity DataIC50: 0.400nMAssay Description:Concentration required for the inhibition of I-125 labeled buserelin binding to the human Gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50120667(Acetic acid 4-(2-{(S)-2-[5-[2-(2-aza-bicyclo[2.2.2...)
Affinity DataIC50: 22nMAssay Description:Concentration required for the inhibition of phosphatidyl inositol hydrolysis in chinese hamster ovary cells expressing human GnRH receptor (Gonadotr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed