BDBM50120481 CHEMBL358541::ethyl 1'-benzylspiro[3,4-dihydro-1H-isochromene-1,4'-(hexahydropyridine)]-3-carboxylate

SMILES CCOC(=O)C1Cc2ccccc2C2(CCN(Cc3ccccc3)CC2)O1

InChI Key InChIKey=QLYZEQUNVZDFRM-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50120481   

TargetSigma non-opioid intracellular receptor 1(Human)
Pharmazeutisches Institut Der Universit£T Freiburg

Curated by ChEMBL
LigandPNGBDBM50120481(ethyl 1'-benzylspiro[3,4-dihydro-1H-isochromene-1,...)
Affinity DataKi:  9.33nMAssay Description:Ability to displace [3H](+)-pentazocine from Sigma opioid receptor type 1 of guinea pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
Pharmazeutisches Institut Der Universit£T Freiburg

Curated by ChEMBL
LigandPNGBDBM50120481(ethyl 1'-benzylspiro[3,4-dihydro-1H-isochromene-1,...)
Affinity DataKi:  1.05E+4nMAssay Description:Ability to displace [3H]ditolylguanidine in the presence of 100 nM (+)-pentazocine from Sigma opioid receptor type 2 of rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed