BDBM50120278 3-(2,4-Dioxo-3,4,5,6,7,8-hexahydro-2H-quinazolin-1-yl)-N-[2-oxo-2-(4-pyrimidin-2-yl-piperazin-1-yl)-ethyl]-propionamide::CHEMBL107260

SMILES O=C(CCn1c2CCCCc2c(=O)[nH]c1=O)NCC(=O)N1CCN(CC1)c1ncccn1

InChI Key InChIKey=GOVHSKFWPFRYIM-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50120278   

TargetPoly [ADP-ribose] polymerase 1(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50120278(3-(2,4-Dioxo-3,4,5,6,7,8-hexahydro-2H-quinazolin-1...)
Affinity DataEC50:  300nMAssay Description:Concentration required to inhibit human recombinant Poly (ADP-ribose) polymerase 1 was determined using cell protection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50120278(3-(2,4-Dioxo-3,4,5,6,7,8-hexahydro-2H-quinazolin-1...)
Affinity DataIC50: 90nMAssay Description:Inhibitory activity against human recombinant PARP-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed