BDBM50120265 3-(2,4-Dioxo-3,4,7,8-tetrahydro-2H,5H-thiopyrano[4,3-d]pyrimidin-1-yl)-N-[2-(4-methoxy-phenyl)-2-oxo-ethyl]-propionamide::3-(2,4-dioxo-2,3,4,5,7,8-hexahydro-1H-thiopyrano[4,3-d]pyrimidin-1-yl)-N-(2-(4-methoxyphenyl)-2-oxoethyl)propanamide::CHEMBL433356

SMILES COc1ccc(cc1)C(=O)CNC(=O)CCn1c2CCSCc2c(=O)[nH]c1=O

InChI Key InChIKey=COPXGNRETUELEB-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50120265   

TargetPoly [ADP-ribose] polymerase 1(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50120265(3-(2,4-dioxo-2,3,4,5,7,8-hexahydro-1H-thiopyrano[4...)
Affinity DataIC50: 25nMAssay Description:Inhibitory activity against human recombinant PARP-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50120265(3-(2,4-dioxo-2,3,4,5,7,8-hexahydro-1H-thiopyrano[4...)
Affinity DataIC50: 25nMAssay Description:Inhibition of human recombinant PARP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50120265(3-(2,4-dioxo-2,3,4,5,7,8-hexahydro-1H-thiopyrano[4...)
Affinity DataEC50:  80nMAssay Description:Concentration required to inhibit human recombinant PARP-1 was determined using cell protection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed