BDBM50120253 Benzoic acid 4-{2-[3-(2,4-dioxo-3,4,7,8-tetrahydro-2H,5H-thiopyrano[4,3-d]pyrimidin-1-yl)-propionylamino]-acetyl}-phenyl ester::CHEMBL108968

SMILES O=C(CCn1c2CCSCc2c(=O)[nH]c1=O)NCC(=O)c1ccc(OC(=O)c2ccccc2)cc1

InChI Key InChIKey=YOLUAAAQXFDLAC-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50120253   

TargetPoly [ADP-ribose] polymerase 1(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50120253(Benzoic acid 4-{2-[3-(2,4-dioxo-3,4,7,8-tetrahydro...)
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against human recombinant PARP-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50120253(Benzoic acid 4-{2-[3-(2,4-dioxo-3,4,7,8-tetrahydro...)
Affinity DataEC50:  500nMAssay Description:Concentration required to inhibit human recombinant PARP-1 was determined using cell protection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed