BDBM50120251 CHEMBL108702::N-[2-(3'-Amino-biphenyl-4-yl)-2-oxo-ethyl]-3-(2,4-dioxo-3,4,7,8-tetrahydro-2H,5H-thiopyrano[4,3-d]pyrimidin-1-yl)-propionamide

SMILES Nc1cccc(c1)-c1ccc(cc1)C(=O)CNC(=O)CCn1c2CCSCc2c(=O)[nH]c1=O

InChI Key InChIKey=POIOVHOBWCSGOH-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50120251   

TargetPoly [ADP-ribose] polymerase 1(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50120251(N-[2-(3'-Amino-biphenyl-4-yl)-2-oxo-ethyl]-3-(2,4-...)
Affinity DataEC50:  70nMAssay Description:Concentration required to inhibit human recombinant Poly (ADP-ribose) polymerase 1 was determined using cell protection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM50120251(N-[2-(3'-Amino-biphenyl-4-yl)-2-oxo-ethyl]-3-(2,4-...)
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against human recombinant PARP-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed