BDBM50120155 C-[(S)-C-((S)-1-Benzhydryl-azetidin-2-yl)-C-(3,5-difluoro-phenyl)]-methylamine::CHEMBL419179

SMILES N[C@H]([C@@H]1CCN1C(c1ccccc1)c1ccccc1)c1cc(F)cc(F)c1

InChI Key InChIKey=SUUJWXLFHRQIRQ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50120155   

TargetNociceptin receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50120155(C-[(S)-C-((S)-1-Benzhydryl-azetidin-2-yl)-C-(3,5-d...)
Affinity DataKi:  105nMAssay Description:Compound was evaluated for increase in [35S]GTP-gamma-S, binding for human ORL1 receptor carried out in CHO cell membranes; Nd: no dataMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50120155(C-[(S)-C-((S)-1-Benzhydryl-azetidin-2-yl)-C-(3,5-d...)
Affinity DataKi:  4.02E+3nMAssay Description:Binding affinity at human opioid receptor kappa 1 was determined by using [3H]diprenorphine radioligand in CHO cell membranes at a concentration of 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50120155(C-[(S)-C-((S)-1-Benzhydryl-azetidin-2-yl)-C-(3,5-d...)
Affinity DataKi:  4.25E+3nMAssay Description:Binding affinity at human opioid receptor mu 1 was determined by using [3H]diprenorphine radioligand in CHO cell membranes at a concentration of 0.12...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50120155(C-[(S)-C-((S)-1-Benzhydryl-azetidin-2-yl)-C-(3,5-d...)
Affinity DataKi:  9.53E+3nMAssay Description:Binding affinity at human opioid receptor delta 1 was determined by using [3H]diprenorphine radioligand in CHO cell membranes at a concentration of 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed