BDBM50119797 1,1'-(decane-1,10-diyl)diquinolinium iodide::1,10-di(1-quinoliniumyl)decane; with diiodide ions::CHEMBL225577::CHEMBL419357

SMILES C(CCCCC[n+]1cccc2ccccc12)CCCC[n+]1cccc2ccccc12

InChI Key InChIKey=YZDRSBRUONQQBH-UHFFFAOYSA-N

Data  4 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50119797   

TargetAcetylcholinesterase(Human)
Charles University

Curated by ChEMBL
LigandPNGBDBM50119797(CHEMBL419357 | 1,10-di(1-quinoliniumyl)decane; wit...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human erythrocyte recombinant AChE by modified Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCholinesterase(Human)
Charles University

Curated by ChEMBL
LigandPNGBDBM50119797(CHEMBL419357 | 1,10-di(1-quinoliniumyl)decane; wit...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human plasmatic BChE by modified Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
LigandPNGBDBM50119797(CHEMBL419357 | 1,10-di(1-quinoliniumyl)decane; wit...)
Affinity DataIC50: 2.10E+4nMAssay Description:The SKCa-blocking action was assessed by its ability to inhibit the after hyperpolarization (AHP) in cultured rat sympathetic neuronesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Charles University

Curated by ChEMBL
LigandPNGBDBM50119797(CHEMBL419357 | 1,10-di(1-quinoliniumyl)decane; wit...)
Affinity DataKi:  40nMAssay Description:Inhibition of human erythrocytes recombinant AChE assessed as dissociation constant for enzyme-inhibitor complexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Charles University

Curated by ChEMBL
LigandPNGBDBM50119797(CHEMBL419357 | 1,10-di(1-quinoliniumyl)decane; wit...)
Affinity DataKi:  60nMAssay Description:Inhibition of human erythrocytes recombinant AChE assessed as dissociation constant for enzyme-inhibitor-substrate complexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50119797(CHEMBL419357 | 1,10-di(1-quinoliniumyl)decane; wit...)
Affinity DataKi:  7.81E+3nMAssay Description:Binding affinity nicotinic acetylcholine receptor alpha-7 was evaluated by its ability to inhibit [3H]methyllycaconitine ([3H]-MLA) binding to rat br...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50119797(CHEMBL419357 | 1,10-di(1-quinoliniumyl)decane; wit...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity for nicotinic acetylcholine receptor alpha4-beta2 was evaluated by its ability to inhibit [3H]NIC binding to rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed