BDBM50119787 1,1''-(octane-1,8-diyl)diquinolinium iodide::1,8-di(1-quinoliniumyl)octane; with diiodide ions::CHEMBL1761995::CHEMBL276745

SMILES C(CCCC[n+]1cccc2ccccc12)CCC[n+]1cccc2ccccc12

InChI Key InChIKey=LGGRUTTWKKNPBL-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50119787   

TargetAcetylcholinesterase(Human)
Charles University

Curated by ChEMBL
LigandPNGBDBM50119787(CHEMBL276745 | 1,1''-(octane-1,8-diyl)diquinoliniu...)
Affinity DataIC50: 80nMAssay Description:Inhibition of human erythrocyte recombinant AChE by modified Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCholinesterase(Human)
Charles University

Curated by ChEMBL
LigandPNGBDBM50119787(CHEMBL276745 | 1,1''-(octane-1,8-diyl)diquinoliniu...)
Affinity DataIC50: 700nMAssay Description:Inhibition of human plasmatic BChE by modified Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50119787(CHEMBL276745 | 1,1''-(octane-1,8-diyl)diquinoliniu...)
Affinity DataKi:  2.39E+3nMAssay Description:Binding affinity nicotinic acetylcholine receptor alpha-7 was evaluated by its ability to inhibit [3H]methyllycaconitine ([3H]-MLA) binding to rat br...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50119787(CHEMBL276745 | 1,1''-(octane-1,8-diyl)diquinoliniu...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity for nicotinic acetylcholine receptor alpha4-beta2 was evaluated by its ability to inhibit [3H]NIC binding to rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed