BDBM50119611 CHEMBL3618235

SMILES Cc1nc(N)nc(n1)-c1c(Nc2ccc3ccncc3c2)nc2ccccn12

InChI Key InChIKey=JBJBXMVUMJDDMK-UHFFFAOYSA-N

Data  1 KI  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50119611   

TargetSerine/threonine-protein kinase mTOR(Human)
Amgen

Curated by ChEMBL

LigandBDBM50119611(CHEMBL3618235)Copy SMILESCopy InChI

Affinity DataIC50: 12nMAssay Description:Inhibition of GST-tagged mTOR (1360 to 2549 residues) (unknown origin) using Ulight 4eBP1 peptide incubated for 90 mins by HTRF assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
12/2/2016
Entry Details Article
Copy Entry DOIPubMed
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Amgen

Curated by ChEMBL

LigandBDBM50119611(CHEMBL3618235)Copy SMILESCopy InChI

Affinity DataKi:  54nMAssay Description:Inhibition of PI3Kalpha (unknown origin) by alpha screen assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
12/2/2016
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL