BDBM50119607 CHEMBL440057::E G P P I S I D L S L E L L R K M I E I E K Q E K E K Q Q A A N N R L L L D T I I-NH2(r/h CRF)::Human corticotropin releasing factor

SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](C)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](N)CO)[C@@H](C)CC)[C@@H](C)O)C(C)C)[C@@H](C)CC)C(O)=O

InChI Key InChIKey=PNMZQWKBJIQQJL-UHFFFAOYSA-N

Data  4 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50119607   

TargetCorticotropin-releasing factor receptor 1(Mouse)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119607(E G P P I S I D L S L E L L R K M I E I E K Q E K ...)
Affinity DataEC50:  20nMAssay Description:In vitro effective concentration for mouse corticotropin releasing factor 1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 2(Mouse)
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50119607(E G P P I S I D L S L E L L R K M I E I E K Q E K ...)
Affinity DataEC50:  49nMAssay Description:In vitro effective concentration for mouse corticotropin releasing factor 2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50119607(E G P P I S I D L S L E L L R K M I E I E K Q E K ...)
Affinity DataIC50: 0.990nMAssay Description:Inhibition of recombinant corticotropin releasing factor receptor 1 assayed using nonselective [125I]-labeled agonist [Tyr0,Glu1,Nle17]-sauvagineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 2(Human)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50119607(E G P P I S I D L S L E L L R K M I E I E K Q E K ...)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of recombinant human corticotropin releasing factor receptor 2 beta (CRF2beta) assayed using nonselective [125I]-labeled agonist [Tyr0,Glu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 2(Rat)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50119607(E G P P I S I D L S L E L L R K M I E I E K Q E K ...)
Affinity DataIC50: 2.10nMAssay Description:Compound was evaluated for affinity towards Corticotropin releasing factor receptor 2 expressing tissues such as Choroid plexus, blood vesselsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50119607(E G P P I S I D L S L E L L R K M I E I E K Q E K ...)
Affinity DataIC50: 12nMAssay Description:Compound was evaluated for affinity towards Corticotropin releasing factor receptor 1 expressing tissues such as Cortex, cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed