BDBM50119552 CHEMBL3617565

SMILES CCC[C@@H]([C@@H](c1c[nH]c2c(F)cc(Cl)cc12)c1ccc(OC(F)(F)F)cc1)c1ccc(cc1)C(=O)NCCC(O)=O

InChI Key InChIKey=BXIHDDDPFHQOPE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50119552   

TargetGlucagon receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50119552(CHEMBL3617565)
Affinity DataIC50: 19nMAssay Description:Antagonist activity at human glucagon receptor expressed in CHO cells assessed as inhibition of glucagon-stimulated intracellular cAMP formation prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2016
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50119552(CHEMBL3617565)
Affinity DataIC50: 0.240nMAssay Description:Displacement of [125I]-glucagon from human glucagon receptor expressed in CHO cells after 4 to 12 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2016
Entry Details Article
PubMed