BDBM50119369 1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid [1-(4-chloro-benzyl)-2-(4-cyclohexyl-4-[1,2,4]triazol-1-ylmethyl-piperidin-1-yl)-2-oxo-ethyl]-amide::CHEMBL140108

SMILES Clc1ccc(C[C@H](NC(=O)[C@@H]2Cc3ccccc3CN2)C(=O)N2CCC(Cn3cncn3)(CC2)C2CCCCC2)cc1

InChI Key InChIKey=HLCHESOMJVGDSJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50119369   

TargetMelanocortin receptor 4(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50119369(1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid ...)
Affinity DataIC50: 127nMAssay Description:Evaluated for Functional Activity at Melanocortin-4 receptor as effective concentration at 50% maximum CMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed