BDBM50119345 (R)-2-((3S,4S)-3-((4-hydroxy-4-(3-phenylpropyl)piperidin-1-yl)methyl)-4-phenylpyrrolidin-1-yl)-3-methylbutanoic acid::2-{3-[4-hydroxy-4-(3-phenylpropyl)hexahydro-1-pyridinylmethyl]-4-phenyltetrahydro-1H-1-pyrrolyl}-3-methylbutanoic acid::CHEMBL318210

SMILES CC(C)[C@@H](N1C[C@H](CN2CCC(O)(CCCc3ccccc3)CC2)[C@H](C1)c1ccccc1)C(O)=O

InChI Key InChIKey=JWVCFPSKCYJGBK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50119345   

TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50119345(2-{3-[4-hydroxy-4-(3-phenylpropyl)hexahydro-1-pyri...)
Affinity DataIC50: 2nMAssay Description:In vitro binding affinity at CCR5 receptor in the presence of [125I]-MIP-1 alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50119345(2-{3-[4-hydroxy-4-(3-phenylpropyl)hexahydro-1-pyri...)
Affinity DataIC50: 2nMAssay Description:Displacement of [125I]MIP1alpha from human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed