BDBM50118981 1-(2-Methoxy-acetyl)-4-[4-(pyridin-4-yloxy)-benzenesulfonyl]-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-3-carboxylic acid hydroxyamide::CHEMBL316489

SMILES COCC(=O)N1CC(N(Cc2ccccc12)S(=O)(=O)c1ccc(Oc2ccncc2)cc1)C(=O)NO

InChI Key InChIKey=UGMUJIKGJCCUOY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50118981   

TargetMatrix metalloproteinase-9(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50118981(1-(2-Methoxy-acetyl)-4-[4-(pyridin-4-yloxy)-benzen...)
Affinity DataIC50: 2nMAssay Description:Concentration required in vitro to inhibit Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50118981(1-(2-Methoxy-acetyl)-4-[4-(pyridin-4-yloxy)-benzen...)
Affinity DataIC50: 763nMAssay Description:Concentration required in vitro to inhibit Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50118981(1-(2-Methoxy-acetyl)-4-[4-(pyridin-4-yloxy)-benzen...)
Affinity DataIC50: 157nMAssay Description:Concentration required in vitro to inhibit TNF-alpha converting enzyme (TACE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50118981(1-(2-Methoxy-acetyl)-4-[4-(pyridin-4-yloxy)-benzen...)
Affinity DataIC50: 2nMAssay Description:Concentration required in vitro to inhibit Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed