BDBM50118970 1-Benzoyl-4-[4-(4-chloro-phenoxy)-benzenesulfonyl]-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-3-carboxylic acid hydroxyamide::CHEMBL330588

SMILES ONC(=O)C1CN(C(=O)c2ccccc2)c2ccccc2CN1S(=O)(=O)c1ccc(Oc2ccc(Cl)cc2)cc1

InChI Key InChIKey=PAAGUAHWPSXIJP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50118970   

TargetMatrix metalloproteinase-9(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50118970(1-Benzoyl-4-[4-(4-chloro-phenoxy)-benzenesulfonyl]...)
Affinity DataIC50: 2nMAssay Description:Concentration required in vitro to inhibit Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50118970(1-Benzoyl-4-[4-(4-chloro-phenoxy)-benzenesulfonyl]...)
Affinity DataIC50: 2nMAssay Description:Concentration required in vitro to inhibit Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50118970(1-Benzoyl-4-[4-(4-chloro-phenoxy)-benzenesulfonyl]...)
Affinity DataIC50: 59nMAssay Description:Concentration required in vitro to inhibit Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50118970(1-Benzoyl-4-[4-(4-chloro-phenoxy)-benzenesulfonyl]...)
Affinity DataIC50: 528nMAssay Description:Concentration required in vitro to inhibit TNF-alpha converting enzyme (TACE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed