BDBM50118771 2-(carboxyformamido)-6-hydroxy-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid::6-Hydroxy-2-(oxalyl-amino)-4,5,6,7-tetrahydro-benzo[b]thiophene-3-carboxylic acid::CHEMBL139356

SMILES OC1CCc2c(C1)sc(NC(=O)C(O)=O)c2C(O)=O

InChI Key InChIKey=VUGHDZNNBFETOT-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50118771   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Graduate University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50118771(6-Hydroxy-2-(oxalyl-amino)-4,5,6,7-tetrahydro-benz...)
Affinity DataKi:  1.99E+3nMAssay Description:Binding affinity to PTP1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Graduate University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50118771(6-Hydroxy-2-(oxalyl-amino)-4,5,6,7-tetrahydro-benz...)
Affinity DataKi:  2.00E+3nMAssay Description:Binding affinity to human recombinant PTP1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Graduate University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50118771(6-Hydroxy-2-(oxalyl-amino)-4,5,6,7-tetrahydro-benz...)
Affinity DataKi:  2.00E+3nMpH: 5.5Assay Description:Inhibitory effect against recombinant human protein-tyrosine phosphatase 1B (PTP1B), using p-nitrophenyl phosphate substrate at pH 5.5.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50118771(6-Hydroxy-2-(oxalyl-amino)-4,5,6,7-tetrahydro-benz...)
Affinity DataKi:  2.15E+5nMpH: 5.5Assay Description:Inhibitory effect against human protein-tyrosine phosphatase alpha (PTPalpha), using p-nitrophenyl phosphate substrate at pH 5.5.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed