BDBM50118370 CHEMBL3612501

SMILES CN(\N=C\c1cnn2ccc(Cl)nc12)S(=O)(=O)c1cc(ccc1Cl)[N+]([O-])=O

InChI Key InChIKey=BQFWZWNBYBXNGJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50118370   

LigandPNGBDBM50118370(CHEMBL3612501)
Affinity DataIC50: 29nMAssay Description:Inhibition of PI3Kalpha (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2016
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Melbourne

Curated by ChEMBL
LigandPNGBDBM50118370(CHEMBL3612501)
Affinity DataIC50: 21nMAssay Description:Inhibition of FLT3 (unknown origin) using biotin-Glu-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2 as substrate after 90 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2016
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
University of Melbourne

Curated by ChEMBL
LigandPNGBDBM50118370(CHEMBL3612501)
Affinity DataIC50: 79nMAssay Description:Inhibition of recombinant human CDK9/cyclin-T1 using H-YSPTSPSYSPTSPSYSPTSPS-KKKK-OH as substrate after 90 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2016
Entry Details Article
PubMed