BDBM50118259 CHEMBL3612506

SMILES COc1ccc(cn1)-c1ccn2ncc(\C=N\N(C)S(=O)(=O)c3cc(ccc3C)[N+]([O-])=O)c2n1

InChI Key InChIKey=JWTRWPDHWSAJPG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50118259   

TargetCyclin-dependent kinase 7(Human)
University of Melbourne

Curated by ChEMBL
LigandPNGBDBM50118259(CHEMBL3612506)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK7 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2016
Entry Details Article
PubMed
LigandPNGBDBM50118259(CHEMBL3612506)
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2016
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
University of Melbourne

Curated by ChEMBL
LigandPNGBDBM50118259(CHEMBL3612506)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human CDK9/cyclin-T1 using H-YSPTSPSYSPTSPSYSPTSPS-KKKK-OH as substrate after 90 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2016
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Melbourne

Curated by ChEMBL
LigandPNGBDBM50118259(CHEMBL3612506)
Affinity DataIC50: 10nMAssay Description:Inhibition of FLT3 (unknown origin) using biotin-Glu-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2 as substrate after 90 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2016
Entry Details Article
PubMed