BDBM50118138 CHEMBL3612840

SMILES Nc1ncc(-c2cnn(CC(=O)N3CCOCC3)c2)c2scc(-c3ccc(Oc4ccccc4)cc3)c12

InChI Key InChIKey=GFOIQLNLIWYHQN-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50118138   

TargetTyrosine-protein kinase BTK(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50118138(CHEMBL3612840)
Affinity DataIC50: 12nMAssay Description:Inhibition of BTK (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50118138(CHEMBL3612840)
Affinity DataIC50: 2.43E+3nMAssay Description:Inhibition of c-MET (unknown origin) after 1 hr by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2016
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50118138(CHEMBL3612840)
Affinity DataIC50: 191nMAssay Description:Inhibition of KDR (unknown origin) after 1 hr by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50118138(CHEMBL3612840)
Affinity DataIC50: 3.07E+3nMAssay Description:Inhibition of JAK3 (unknown origin) after 1 hr by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50118138(CHEMBL3612840)
Affinity DataIC50: 6.86E+3nMAssay Description:Inhibition of JAK2 (unknown origin) after 1 hr by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2016
Entry Details Article
PubMed