BDBM50118096 2,2'-(4,4'-(1,4-phenylenebis(methylene))bis(oxy)bis(4,1-phenylene))bis(2-oxoacetic acid)::CHEMBL129681::{4-[4-(4-Oxalyl-phenoxymethyl)-benzyloxy]-phenyl}-oxo-acetic acid

SMILES OC(=O)C(=O)c1ccc(OCc2ccc(COc3ccc(cc3)C(=O)C(O)=O)cc2)cc1

InChI Key InChIKey=HNHFGJRWYYEILT-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50118096   

TargetReceptor-type tyrosine-protein phosphatase C(Human)
Brown University

Curated by ChEMBL
LigandPNGBDBM50118096({4-[4-(4-Oxalyl-phenoxymethyl)-benzyloxy]-phenyl}-...)
Affinity DataIC50: 700nMAssay Description:Concentration required for 50% Inhibition of activity against Yersinia Protein-tyrosine phosphataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
Brown University

Curated by ChEMBL
LigandPNGBDBM50118096({4-[4-(4-Oxalyl-phenoxymethyl)-benzyloxy]-phenyl}-...)
Affinity DataIC50: 2.50E+5nMAssay Description:Concentration required for 50% Inhibition of activity against Protein-tyrosine phosphatase LarMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Brown University

Curated by ChEMBL
LigandPNGBDBM50118096({4-[4-(4-Oxalyl-phenoxymethyl)-benzyloxy]-phenyl}-...)
Affinity DataIC50: 2.70E+3nMAssay Description:Concentration required for 50% Inhibition of activity against Protein Tyrosine Phosphatases 1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Brown University

Curated by ChEMBL
LigandPNGBDBM50118096({4-[4-(4-Oxalyl-phenoxymethyl)-benzyloxy]-phenyl}-...)
Affinity DataIC50: 5.73E+3nMAssay Description:Inhibition of PTP1B by pNPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50118096({4-[4-(4-Oxalyl-phenoxymethyl)-benzyloxy]-phenyl}-...)
Affinity DataIC50: 5.35E+3nMAssay Description:Inhibition of TCPTP by pNPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Brown University

Curated by ChEMBL
LigandPNGBDBM50118096({4-[4-(4-Oxalyl-phenoxymethyl)-benzyloxy]-phenyl}-...)
Affinity DataIC50: 3.89E+3nMAssay Description:Inhibition of GST-tagged human PTP 1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50118096({4-[4-(4-Oxalyl-phenoxymethyl)-benzyloxy]-phenyl}-...)
Affinity DataIC50: 6.24E+3nMAssay Description:Inhibition of GST-tagged human TCPTPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50118096({4-[4-(4-Oxalyl-phenoxymethyl)-benzyloxy]-phenyl}-...)
Affinity DataIC50: 6.24E+3nMAssay Description:Inhibition of TCPTP by para-nitrophenyl phosphate release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Brown University

Curated by ChEMBL
LigandPNGBDBM50118096({4-[4-(4-Oxalyl-phenoxymethyl)-benzyloxy]-phenyl}-...)
Affinity DataIC50: 3.89E+3nMAssay Description:Inhibition of PTP1B by para-nitrophenyl phosphate release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Brown University

Curated by ChEMBL
LigandPNGBDBM50118096({4-[4-(4-Oxalyl-phenoxymethyl)-benzyloxy]-phenyl}-...)
Affinity DataIC50: 5.73E+3nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Brown University

Curated by ChEMBL
LigandPNGBDBM50118096({4-[4-(4-Oxalyl-phenoxymethyl)-benzyloxy]-phenyl}-...)
Affinity DataIC50: 5.73E+3nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article