BDBM50117731 3-Isobutyl-1-methyl-8-(2-propoxy-phenyl)-3,7-dihydro-purine-2,6-dione::CHEMBL87901

SMILES CCCOc1ccccc1-c1nc2n(CC(C)C)c(=O)n(C)c(=O)c2[nH]1

InChI Key InChIKey=RLYZANWBRWYOIA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50117731   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50117731(3-Isobutyl-1-methyl-8-(2-propoxy-phenyl)-3,7-dihyd...)
Affinity DataIC50: 60nMAssay Description:Inhibitory activity against human platelet Phosphodiesterase 5 (PDE5)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50117731(3-Isobutyl-1-methyl-8-(2-propoxy-phenyl)-3,7-dihyd...)
Affinity DataIC50: 87nMAssay Description:Inhibitory concentration against bovine retina phosphodiesterase 6 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed