BDBM50117722 CHEMBL89239::N-(2-Dimethylamino-ethyl)-3-(3-isobutyl-1-methyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)-N-methyl-4-propoxy-benzenesulfonamide

SMILES CCCOc1ccc(cc1-c1nc2n(CC(C)C)c(=O)n(C)c(=O)c2[nH]1)S(=O)(=O)N(C)CCN(C)C

InChI Key InChIKey=VASZTWPERWJCNH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50117722   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50117722(N-(2-Dimethylamino-ethyl)-3-(3-isobutyl-1-methyl-2...)
Affinity DataIC50: 16nMAssay Description:Inhibitory activity against human platelet Phosphodiesterase 5 (PDE5)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50117722(N-(2-Dimethylamino-ethyl)-3-(3-isobutyl-1-methyl-2...)
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibitory concentration against bovine retina phosphodiesterase 6 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed