BDBM50117720 8-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phenyl]-3-hexyl-1-methyl-3,7-dihydro-purine-2,6-dione::CHEMBL313561

SMILES CCCCCCn1c2nc([nH]c2c(=O)n(C)c1=O)-c1cc(ccc1OCC)S(=O)(=O)N1CCN(C)CC1

InChI Key InChIKey=JYNJCYRMTVRPMA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50117720   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50117720(8-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50: 130nMAssay Description:Inhibitory activity against human platelet Phosphodiesterase 5 (PDE5)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed