BDBM50117665 CHEMBL3613709

SMILES COc1cccc(CC(=O)N2Cc3ccc(cc3C2)S(=O)(=O)Nc2cnn(n2)C2CCC2)c1

InChI Key InChIKey=GRXCLNMCJWKTAT-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50117665   

LigandPNGBDBM50117665(CHEMBL3613709)
Affinity DataIC50: 92nMAssay Description:Inhibition of MGAT3 (unknown origin) assessed effect on incorporation of [1-14C]decanoyl moiety into triacylglycerol using [1-14C]decanoyl-CoA and 1,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandPNGBDBM50117665(CHEMBL3613709)
Affinity DataIC50: 100nMAssay Description:Inhibition of MGAT3 (unknown origin) assessed effect on incorporation of [1-14C]decanoyl moiety into triacylglycerol using [1-14C]decanoyl-CoA and 1,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandPNGBDBM50117665(CHEMBL3613709)
Affinity DataIC50: 1.49E+4nMAssay Description:Inhibition of MGAT1 (unknown origin) assessed as effect on incorporation of [1-14C]decanoyl moiety into DAG using [1-14C]decanoyl-CoA and 2-oleoylgly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandPNGBDBM50117665(CHEMBL3613709)
Affinity DataIC50: 1.48E+4nMAssay Description:Inhibition of MGAT1 (unknown origin) assessed as effect on incorporation of [1-14C]decanoyl moiety into DAG using [1-14C]decanoyl-CoA and 2-oleoylgly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandPNGBDBM50117665(CHEMBL3613709)
Affinity DataIC50: 1.98E+4nMAssay Description:Inhibition of MGAT2 (unknown origin) assessed as effect on incorporation of [1-14C]decanoyl moiety into DAG using [1-14C]decanoyl-CoA and 1-decanoyl-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandPNGBDBM50117665(CHEMBL3613709)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of MGAT2 (unknown origin) assessed as effect on incorporation of [1-14C]decanoyl moiety into DAG using [1-14C]decanoyl-CoA and 1-decanoyl-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50117665(CHEMBL3613709)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of DGAT1 (unknown origin) assessed as effect on incorporation of [1-14C]decanoyl moiety into TG using [1-14C]decanoyl-CoA and 1,2-didecano...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50117665(CHEMBL3613709)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of DGAT2 (unknown origin) using [1-14C]decanoyl-CoA and didecanoyl-sn-glycerol substrates incubated for 40 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandPNGBDBM50117665(CHEMBL3613709)
Affinity DataIC50: 205nMAssay Description:Inhibition of human MGAT3 expressed in HEK293 cells assessed as effect on incorporation of [1,3-14C] glycerol into TAG by TLC method in presence of D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandPNGBDBM50117665(CHEMBL3613709)
Affinity DataIC50: 204nMAssay Description:Inhibition of human MGAT3 expressed in HEK293 cells assessed as effect on incorporation of [1,3-14C] glycerol into TAG by TLC method in presence of D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
LigandPNGBDBM50117665(CHEMBL3613709)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of PPARgamma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed