BDBM50117380 4-{6-Methoxy-7-[3-(3-methyl-butane-1-sulfonyl)-propoxy]-quinazolin-4-yl}-piperazine-1-carboxylic acid (4-isopropoxy-phenyl)-amide::CHEMBL339403

SMILES COc1cc2c(ncnc2cc1OCCCS(=O)(=O)CCC(C)C)N1CCN(CC1)C(=O)Nc1ccc(OC(C)C)cc1

InChI Key InChIKey=WTFQTDJXZDGOHR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50117380   

TargetPlatelet-derived growth factor receptor beta(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50117380(4-{6-Methoxy-7-[3-(3-methyl-butane-1-sulfonyl)-pro...)
Affinity DataIC50: 50nMAssay Description:Inhibition of platelet-derived growth factor receptor beta phosphorylation in MG63 cells in the absence of plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50117380(4-{6-Methoxy-7-[3-(3-methyl-butane-1-sulfonyl)-pro...)
Affinity DataIC50: 240nMAssay Description:Inhibition of platelet derived growth factor receptor beta phosphorylation in MG63 cells in the presence of human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed