BDBM50117204 4-[(7-Chloro-3-methyl-4-oxo-2-piperidin-1-ylmethyl-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-N-pyridin-3-ylmethyl-benzamide::CHEMBL333094

SMILES Cn1c(CN2CCCCC2)nc2cc(Cl)c(CN(CC#C)c3ccc(cc3)C(=O)NCc3cccnc3)cc2c1=O

InChI Key InChIKey=DCDSBGMXFVLYHN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50117204   

TargetThymidylate synthase(Mouse)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50117204(4-[(7-Chloro-3-methyl-4-oxo-2-piperidin-1-ylmethyl...)
Affinity DataIC50: 50nMAssay Description:Growth inhibitory activity against mouse lymphoblastoid L1210TS cell line was determined as inhibition of thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed