BDBM50116938 1-{5-[4-(2-Phenoxy-phenyl)-piperazin-1-ylmethyl]-isoxazol-3-ylmethyl}-piperidin-2-one::CHEMBL81661

SMILES O=C1CCCCN1Cc1cc(CN2CCN(CC2)c2ccccc2Oc2ccccc2)on1

InChI Key InChIKey=YEVKDYPUKCQOFQ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50116938   

TargetAlpha-1A adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50116938(1-{5-[4-(2-Phenoxy-phenyl)-piperazin-1-ylmethyl]-i...)
Affinity DataKi:  15nMAssay Description:Displacement of [125I]HEAT from human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50116938(1-{5-[4-(2-Phenoxy-phenyl)-piperazin-1-ylmethyl]-i...)
Affinity DataKi:  170nMAssay Description:Displacement of [125I]HEAT from human Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50116938(1-{5-[4-(2-Phenoxy-phenyl)-piperazin-1-ylmethyl]-i...)
Affinity DataKi:  2.21E+3nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed