BDBM50116931 1-{5-[4-(2-Phenoxy-phenyl)-piperazin-1-ylmethyl]-isoxazol-3-ylmethyl}-azepan-2-one::CHEMBL79817

SMILES O=C1CCCCCN1Cc1cc(CN2CCN(CC2)c2ccccc2Oc2ccccc2)on1

InChI Key InChIKey=ZJEHREFWDSGYHV-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50116931   

TargetAlpha-1A adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50116931(1-{5-[4-(2-Phenoxy-phenyl)-piperazin-1-ylmethyl]-i...)
Affinity DataKi:  86nMAssay Description:Displacement of [125I]HEAT from human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50116931(1-{5-[4-(2-Phenoxy-phenyl)-piperazin-1-ylmethyl]-i...)
Affinity DataKi:  285nMAssay Description:Displacement of [125I]HEAT from human Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50116931(1-{5-[4-(2-Phenoxy-phenyl)-piperazin-1-ylmethyl]-i...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [125I]-HEAT from human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed