BDBM50116765 3-Propyl-1,2,3,4-tetrahydro-3,8a,9-triaza-fluorene::CHEMBL80845

SMILES CCCN1CCc2nn3ccccc3c2C1

InChI Key InChIKey=URWBDIMBZFWGSF-UHFFFAOYSA-N

Data  6 KI  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50116765   

TargetD(2) dopamine receptor(Rat)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50116765(3-Propyl-1,2,3,4-tetrahydro-3,8a,9-triaza-fluorene...)
Affinity DataEC50: >1.00E+3nMAssay Description:Effective concentration required for agonistic activity against rat D2 short receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50116765(3-Propyl-1,2,3,4-tetrahydro-3,8a,9-triaza-fluorene...)
Affinity DataEC50: >1.00E+3nMAssay Description:Effective concentration required for agonistic activity against rat D2 long receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50116765(3-Propyl-1,2,3,4-tetrahydro-3,8a,9-triaza-fluorene...)
Affinity DataEC50: >1.00E+3nMAssay Description:Effective concentration required for agonistic activity against human D3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50116765(3-Propyl-1,2,3,4-tetrahydro-3,8a,9-triaza-fluorene...)
Affinity DataEC50: >1.00E+3nMAssay Description:Effective concentration required for agonistic activity against human D4.2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50116765(3-Propyl-1,2,3,4-tetrahydro-3,8a,9-triaza-fluorene...)
Affinity DataKi:  16nMAssay Description:Binding affinity of compound measured using [3H]spiperone for the cloned human Dopamine receptor D3 (high/low affinity is given as 16/16000)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50116765(3-Propyl-1,2,3,4-tetrahydro-3,8a,9-triaza-fluorene...)
Affinity DataKi:  87nMAssay Description:Binding affinity of compound measured using [3H]spiperone for the cloned human dopamine receptor D4.4 (high/low affinity is given as 87/23000)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50116765(3-Propyl-1,2,3,4-tetrahydro-3,8a,9-triaza-fluorene...)
Affinity DataKi:  130nMAssay Description:Binding affinity of compound measured using [3H]spiperone for the cloned human dopamine receptor D2 short (high/low affinity is given as 130/50000)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50116765(3-Propyl-1,2,3,4-tetrahydro-3,8a,9-triaza-fluorene...)
Affinity DataKi:  230nMAssay Description:Binding affinity of compound measured using [3H]spiperone for the cloned human dopamine receptor D2 long (high/low affinity is given as 230/53000)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50116765(3-Propyl-1,2,3,4-tetrahydro-3,8a,9-triaza-fluorene...)
Affinity DataKi:  3.10E+3nMAssay Description:Binding affinity of compound against Dopamine receptor D2 was measured using [3H]pramipexole in Bovine striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Bovine)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50116765(3-Propyl-1,2,3,4-tetrahydro-3,8a,9-triaza-fluorene...)
Affinity DataKi:  2.10E+4nMAssay Description:Binding affinity of compound measured against Dopamine receptor D1 from bovine striatal membranes using radioligand [3H]-SCH- 23390More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed