BDBM50116722 CHEMBL263243::N-{(R)-5-{4-[3-((R)-1-Carbamoyl-2-hydroxy-ethyl)-2-oxo-tetrahydro-pyrimidin-1-yl]-piperidin-1-yl}-3-(3,4-dichloro-phenyl)-2-[(Z)-methoxyimino]-pentyl}-3,5-dichloro-N-methyl-benzamide

SMILES CO\N=C(/CN(C)C(=O)c1cc(Cl)cc(Cl)c1)[C@H](CCN1CCC(CC1)N1CCCN([C@H](CO)C(N)=O)C1=O)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=ROETYKQAPNITRN-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50116722   

TargetNeuromedin-K receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50116722(N-{(R)-5-{4-[3-((R)-1-Carbamoyl-2-hydroxy-ethyl)-2...)
Affinity DataKi:  0.300nMAssay Description:Binding affinity against recombinant human tachykinin receptor 3 in CHO cells using [125I][MePhe]-NKB as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50116722(N-{(R)-5-{4-[3-((R)-1-Carbamoyl-2-hydroxy-ethyl)-2...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity against recombinant human tachykinin receptor 2 in CHO cells using [3H]-NKA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50116722(N-{(R)-5-{4-[3-((R)-1-Carbamoyl-2-hydroxy-ethyl)-2...)
Affinity DataKi:  0.600nMAssay Description:Binding affinity against recombinant human tachykinin receptor 1 in CHO cells using [3H]-Sar SP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed