BDBM50116514 CHEMBL507522

SMILES [H][C@@]12C[C@@]1(Oc1ccccc1\C2=N\O)C(=O)Nc1ccccc1

InChI Key InChIKey=FPXPIEZPAXSELW-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50116514   

TargetMetabotropic glutamate receptor 4(Human)
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50116514(CHEMBL507522)
Affinity DataEC50:  1.40E+3nMAssay Description:Positive allosteric modulator activity at mGlu4 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50116514(CHEMBL507522)
Affinity DataEC50:  2.25E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Massachusetts General Hospital

Curated by ChEMBL
LigandPNGBDBM50116514(CHEMBL507522)
Affinity DataEC50:  2.50E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing chimeric G protein assessed as increase in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2019
Entry Details Article
PubMed